Friday, May 31, 2013

Correction: Music Review-Wagner at the Met

In a review May 28 about the "Wagner at the Met: Legendary Performances from The Metropolitan Opera" box set, The Associated Press erroneously left out the first name of performer Kirsten Flagstad. The review also transposed her last name with that of Astrid Varnay in a reference to "Siegmund! Sieh' auf mich! (Siegmund! Look at me!)."

A corrected version of the story is below:

By RON BLUM

Associated Press

Various Artists, "Wagner at the Met: Legendary Performances from The Metropolitan Opera" (Sony Classical)

Yes, there really was a golden age, and this was it.

To mark the 200th anniversary of Richard Wagner's birth on May 22, a 25-disc set taken from the archives of Saturday afternoon Metropolitan Opera broadcasts documents performances of nine of the composer's 10 mature works ? "Parsifal" was excluded. The recordings date from 1936-54 and while some of these had appeared previously on CD, these are the first authorized releases. The sound from the original lacquers and tapes has been improved and cleaned markedly, but don't expect the clarity, depth and width of the digital era, especially from the 1930s broadcasts. And the conductors of the day made cuts that would be unacceptable to the 21st century Met audience.

But, oh, the singing.

Hans Hotter's booming Dutchman from "Die Fliegende Hollaender" is paired with Astrid Varnay's excitable Senta under Fritz Reiner's baton from 1950. George Szell's "Tannhaeuser" from 1954 shows interesting tempi choices in the overture, which includes a sudden speedup in the Venusberg theme.

Ramon Vinay's clarion tenor is featured as Tannhaeuser, this time matched with Varnay's sultry Venus, Margaret Harshaw's hefty Elisabeth and a young Roberta Peters as the Shepherd.

For a 1943 "Lohengrin," a fresher-sounding Varnay's Elsa is together with Lauritz Melchior in the title role under Erich Leinsdorf's baton that emphasized flow over energy. Melchior's "In fernem land (In a far-off land)" is a model of diction, breath control, pacing, color and inflection.

Melchior is a central part of the Ring Cycle, as Siegmund in a 1940 "Die Walkuere" with Marjorie Lawrence's Sieglinde, Kirsten Flagstad's Bruennhilde and Julius Huehn's Wotan (under Leinsdorf), a 1937 "Siegfried" with Flagstad and Freidrich Schorr's Wanderer (under Bodanzsky) and a 1936 "Goetterdaemmerung" with Lawrence (again under Bodanzsky).

Melchior's seemingly effortless soft singing in "Winterstuerme (Wintry storms)" highlights how often the role is shouted these days by tenors lacking his technique, and Lawrence's "Du bist der Lenz (You are the spring)" builds tension and pace along with Sieglinde's ardor. Flagstad combines iciness and affection in her opening "Siegmund! Sieh' auf mich! (Siegmund! Look at me!)" from the Todesverkuendigung (Annunciation of death). While Huehn's "Leb' wohl (Farewell)" is low on emotion, Flagstad and Melchior sparkle in the closing duet from "Siegfried."

A 1938 "Tristan und Isolde" with Melchior, Flagstad and Bodanzsky reveals an incendiary love duet that lifts the opera to an even higher level, and Flagstad follows with an ecstatic, mournful Liebestod (lovedeath), although here the thin sound of the recording detracts.

Finally, there is a "Die Meistersinger von Nuernberg" from 1953. Reiner carefully blended Hans Hopf's lyrical Walther, Paul Schoeffler's thick-voiced Sachs and Victoria de los Angeles' sweet and innocent Eva.

While Sony had released 20 individual sets of Met broadcasts in recent years, including a 1968 "Walkuere" and 1972 "Meistersinger," the historic recordings have far more impact when packaged together here. A similar Verdi set is planned for the fall.

Source: http://news.yahoo.com/correction-music-review-wagner-met-200850101.html

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APNewsBreak: OSU head jabs Notre Dame, Catholics

This photo made Sunday, May 5, 2013, shows Ohio State president E. Gordon Gee gesturing as he speaks during the Ohio State University spring commencement in Columbus, Ohio. Gee told a university committee last December that Notre Dame wasn?t invited to join the Big Ten because they?re not good partners while also jokingly saying that ?those damn Catholics? can?t be trusted. (AP Photo/Carolyn Kaster)

This photo made Sunday, May 5, 2013, shows Ohio State president E. Gordon Gee gesturing as he speaks during the Ohio State University spring commencement in Columbus, Ohio. Gee told a university committee last December that Notre Dame wasn?t invited to join the Big Ten because they?re not good partners while also jokingly saying that ?those damn Catholics? can?t be trusted. (AP Photo/Carolyn Kaster)

This photo made Sunday, May 5, 2013, shows Ohio State president E. Gordon Gee during the Ohio State University spring commencement in Columbus, Ohio. Gee told a university committee last December that Notre Dame wasn?t invited to join the Big Ten because they?re not good partners while also jokingly saying that ?those damn Catholics? can?t be trusted. (AP Photo/Carolyn Kaster)

(AP) ? The president of Ohio State University said Notre Dame was never invited to join the Big Ten because the university's priests are not good partners, joking that "those damn Catholics" can't be trusted, according to a recording of a meeting he attended late last year.

At the December meeting of the school's Athletic Council, Gordon Gee also took shots at schools in the Southeastern Conference and the University of Louisville, according to the recording, obtained by The Associated Press under a public records request.

The university called the statements inappropriate and said Gee is undergoing a "remediation plan" because of the remarks.

Gee apologized in a statement released to the AP.

"The comments I made were just plain wrong, and in no way do they reflect what the university stands for," he said. "They were a poor attempt at humor and entirely inappropriate."

Gee, who has taken heat previously for uncouth remarks, told members of the council that he negotiated with Notre Dame officials during his first term at Ohio State, which began more than two decades ago.

"The fathers are holy on Sunday, and they're holy hell on the rest of the week," Gee said to laughter at the Dec. 5 meeting attended by Athletic Director Gene Smith and several other athletic department members, along with professors and students.

"You just can't trust those damn Catholics on a Thursday or a Friday, and so, literally, I can say that," said Gee, a Mormon.

The Big Ten had for years courted Notre Dame, but the school resisted, seeking to retain its independent status in college football. The school announced in September that it would join the Atlantic Coast Conference in all sports except football. It also agreed to play five football games each year against ACC teams.

In the recording, Gee referred specifically to dealing with the Rev. Ned Joyce, Notre Dame's longtime chief financial officer, who died in 2004.

"Father Joyce was one of those people who ran the university for many, many years," Gee said.

Gee said the Atlantic Coast Conference added Notre Dame at a time when it was feeling vulnerable.

"Notre Dame wanted to have its cake and eat it, too," Gee said, according to the recording and a copy of the meeting's minutes.

Gee was introduced by Athletic Council then-chairman Charlie Wilson, and Gee's name and introduction are included in written minutes of the meeting. Gee's comments drew laughter, at times loud, occasionally nervous, but no rebukes, according to the audio.

The Athletic Council meets monthly during the fall, winter and spring and makes recommendations on athletic policy including ticket prices. December's meeting was at Ohio Stadium.

Ohio State trustees learned of "certain offensive statements" by Gee in January, met with the president at length and created the remediation plan for Gee to "address his behavior," board president Robert Schottenstein said in a statement.

"These statements were inappropriate, were not presidential in nature and do not comport with the core values of the University," Schottenstein said.

Gee has gotten in trouble for his offhand remarks, most recently during a memorabilia-for-cash and tattoos scandal that cost football coach Jim Tressel his job. Tressel had known about allegations that players were trading game paraphernalia for money and tattoos but didn't tell the university in violation of his contract and NCAA regulations.

Gee was asked in March 2011 whether he had considered firing Tressel. He responded: "No, are you kidding? Let me just be very clear: I'm just hopeful the coach doesn't dismiss me." Tressel stepped down three months later.

In November 2010, Gee boasted that Ohio State's football schedule didn't include teams on par with the "Little Sisters of the Poor." An apologetic Gee later sent a personal check to the real Little Sisters of the Poor in northwest Ohio and followed up with a visit to the nuns months later.

Last year, Gee apologized for comparing the problem of coordinating the school's many divisions to the Polish army, an off-the-cuff remark that a Polish-American group called a "slanderous" display of bigotry and ignorance.

Gee has one of the highest-profile resumes of any college president in recent history. He has held the top job at West Virginia University, the University of Colorado, Brown University and Vanderbilt University. He was Ohio State president from 1990 to 1997, and returned in 2007. He earns about $1.9 million annually in base pay, deferred and performance compensation and retirement benefits.

He is a prolific fundraiser and is leading a $2.5 billion campaign at Ohio State. He is omnipresent on campus, attending everything from faculty awards events to dormitory pizza parties. He is known for his bow ties ? he has hundreds ? and his horn-rimmed glasses.

During his comments to the Athletic Council, Gee also questioned the academic integrity of schools in the Southeastern Conference, and the University of Louisville.

The top goal of Big Ten presidents is to "make certain that we have institutions of like-minded academic integrity," Gee said. "So you won't see us adding Louisville," a member of the Big East conference that is also joining the ACC.

After a pause followed by laughter from the audience, Gee added that the Big Ten wouldn't add the University of Kentucky, either.

During the meeting, Gee also said he thought it was a mistake not to include Missouri and Kansas in earlier Big Ten expansion plans. Missouri has since joined the SEC.

"You tell the SEC when they can learn to read and write, then they can figure out what we're doing," Gee said, when asked by a questioner how to respond to SEC fans who say the Big Ten can't count because it now has 14 members.

Gee noted he was chairman of the SEC during his time as Vanderbilt University chancellor. He also told his audience that speculation about the SEC "remains right here," according to the recording.

Gee took a swipe at Big Ten Commissioner Jim Delaney, one of the most powerful leaders in college athletics, when he answered a question about preserving Ohio State's financial interests in light of Big Ten revenue-sharing plans.

"No one admires Jim Delaney more than I do ? I chaired the committee that brought him here," Gee said. "Jim is very aggressive, and we need to make certain he keeps his hands out of our pockets while we support him."

___

Associated Press writer John Seewer in Toledo contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-05-30-Ohio%20State%20President/id-08e1a50041aa48288481ad24dbf87c46

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Video: Is Russell distraction worth the risk?

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Source: http://nbcsports.msnbc.com/id/21134540/vp/52034743#52034743

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Patron finds gun on Disney World ride

LAKE BUENA VISTA, Fla. (AP) ? A Walt Disney World patron on a ride with her grandson found a loaded gun on her seat, officials said Wednesday.

Officials said that the woman found the pistol on the Dinosaur ride at Animal Kingdom. The woman turned over the loaded weapon to a park attendant, who then contacted her manager and authorities.

The gun's owner, Angelo Lista, told authorities he discovered his gun was missing several minutes after leaving the ride. He has a concealed weapons permit.

Lista told authorities he didn't know Disney World patrons weren't allowed to bring guns. He said he thought the security checkpoint at the entrance to the Florida theme park was only so that guards could check bags for bombs or explosives. Patrons do not walk through metal detectors nor are they subject to patdowns.

Disney World prohibits patrons from bringing weapons of any kind on its property.

Source: http://news.yahoo.com/disney-world-patron-finds-gun-ride-204422359.html

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A newly discovered hormone makes ovaries grow

A newly discovered hormone makes ovaries grow [ Back to EurekAlert! ] Public release date: 30-May-2013
[ | E-mail | Share Share ]

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology

The FASEB Journal suggests that human female eggs produce a previously unknown hormone, called R-spondin2, which promotes follicle development and stimulates ovary growth

Bethesda, MDA newly discovered hormone produced by the eggs of human females may improve the effectiveness of current fertility treatments for women and possibly lead to entirely new treatments altogether. According to new research published in the June 2013 issue of The FASEB Journal, researchers from Stanford and Akira University in Japan identified a new hormone called "R-spondin2" that promotes follicle development and stimulates ovary growth.

"The finding of a new ovarian hormone produced by the oocytes capable of stimulating ovarian follicle growth could lead to new infertility treatments," said Aaron J. W. Hsueh, Ph.D., a researcher involved in the work from the Division of Reproductive and Stem Cell Biology in the Department of Obstetrics and Genecology at Stanford University Medical School in Stanford, California.

To make this discovery, Hsueh and colleagues analyzed all the proteins likely made by the eggs, and discovered a previously unknown hormone, called R-spondin2. The researchers then replicated this new hormone in test tubes and injected it into mice. The hormone stimulated growth of mouse ovarian cells, leading to the generation of mature eggs. These eggs were fertilized and led to successful pregnancies and the delivery of healthy pups. Then, human ovarian tissue was grafted into mice, and this also grew after treatment with this newly identified ovarian hormone, suggesting that the hormone could work in humans. The researchers speculate that when used in conjunction with the traditional Follicle Stimulating Hormone (FSH), this newly discovered ovarian hormone could lead to new infertility treatment options for those not responding well to FSH treatment alone.

"Infertility can be very frustrating for couples who have been trying to conceive for a very long time. The discovery of this new hormone is a potential game-changer in human fertility treatment," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "but further research is needed to determine its efficacy and safety in humans."

###

Receive monthly highlights from The FASEB Journal by e-mail. Sign up at http://www.faseb.org/fjupdate.aspx. The FASEB Journal is published by the Federation of the American Societies for Experimental Biology (FASEB). It is among the most cited biology journals worldwide according to the Institute for Scientific Information and has been recognized by the Special Libraries Association as one of the top 100 most influential biomedical journals of the past century.

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to its member societies and through collaborative advocacy.

Details: Yuan Cheng, Kazuhiro Kawamura, Seido Takae, Masashi Deguchi, Qing Yang, Calvin Kuo, and Aaron J. W. Hsueh. Oocyte-derived R-spondin2 promotes ovarian follicle development. FASEB J June 2013 27:2175-2184 ; doi:10.1096/fj.12-223412 ; http://www.fasebj.org/content/27/6/2175.abstract


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


A newly discovered hormone makes ovaries grow [ Back to EurekAlert! ] Public release date: 30-May-2013
[ | E-mail | Share Share ]

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology

The FASEB Journal suggests that human female eggs produce a previously unknown hormone, called R-spondin2, which promotes follicle development and stimulates ovary growth

Bethesda, MDA newly discovered hormone produced by the eggs of human females may improve the effectiveness of current fertility treatments for women and possibly lead to entirely new treatments altogether. According to new research published in the June 2013 issue of The FASEB Journal, researchers from Stanford and Akira University in Japan identified a new hormone called "R-spondin2" that promotes follicle development and stimulates ovary growth.

"The finding of a new ovarian hormone produced by the oocytes capable of stimulating ovarian follicle growth could lead to new infertility treatments," said Aaron J. W. Hsueh, Ph.D., a researcher involved in the work from the Division of Reproductive and Stem Cell Biology in the Department of Obstetrics and Genecology at Stanford University Medical School in Stanford, California.

To make this discovery, Hsueh and colleagues analyzed all the proteins likely made by the eggs, and discovered a previously unknown hormone, called R-spondin2. The researchers then replicated this new hormone in test tubes and injected it into mice. The hormone stimulated growth of mouse ovarian cells, leading to the generation of mature eggs. These eggs were fertilized and led to successful pregnancies and the delivery of healthy pups. Then, human ovarian tissue was grafted into mice, and this also grew after treatment with this newly identified ovarian hormone, suggesting that the hormone could work in humans. The researchers speculate that when used in conjunction with the traditional Follicle Stimulating Hormone (FSH), this newly discovered ovarian hormone could lead to new infertility treatment options for those not responding well to FSH treatment alone.

"Infertility can be very frustrating for couples who have been trying to conceive for a very long time. The discovery of this new hormone is a potential game-changer in human fertility treatment," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "but further research is needed to determine its efficacy and safety in humans."

###

Receive monthly highlights from The FASEB Journal by e-mail. Sign up at http://www.faseb.org/fjupdate.aspx. The FASEB Journal is published by the Federation of the American Societies for Experimental Biology (FASEB). It is among the most cited biology journals worldwide according to the Institute for Scientific Information and has been recognized by the Special Libraries Association as one of the top 100 most influential biomedical journals of the past century.

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to its member societies and through collaborative advocacy.

Details: Yuan Cheng, Kazuhiro Kawamura, Seido Takae, Masashi Deguchi, Qing Yang, Calvin Kuo, and Aaron J. W. Hsueh. Oocyte-derived R-spondin2 promotes ovarian follicle development. FASEB J June 2013 27:2175-2184 ; doi:10.1096/fj.12-223412 ; http://www.fasebj.org/content/27/6/2175.abstract


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/foas-and053013.php

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Gene therapy gives mice broad protection to pandemic flu strains, including 1918 flu

May 29, 2013 ? Researchers at the Perelman School of Medicine, University of Pennsylvania have developed a new gene therapy to thwart a potential influenza pandemic. Specifically, investigators in the Gene Therapy Program, Department of Pathology and Laboratory Medicine, directed by James M. Wilson, MD, PhD, demonstrated that a single dose of an adeno-associated virus (AAV) expressing a broadly neutralizing flu antibody into the nasal passages of mice and ferrets gives them complete protection and substantial reductions in flu replication when exposed to lethal strains of H5N1 and H1N1 flu virus. These strains were isolated from samples associated from historic human pandemics -- one from the infamous 1918 flu pandemic and another from 2009.

Wilson, Anna Tretiakova, PhD, Senior Research Scientist, Maria P. Limberis, PhD, Research Assistant Professor, all from the Penn Gene Therapy Program, and colleagues published their findings online this week in Science Translational Medicine ahead of print. In addition to the Penn scientists, the international effort included colleagues from the Public Health Agency of Canada, Winnipeg; the University of Manitoba, Winnipeg; and the University of Pittsburgh. Tretiakova is also the director of translational research, and Limberis is the director of animal models core, both with the Gene Therapy Program.

"The experiments described in our paper provide critical proof-of-concept in animals about a technology platform that can be deployed in the setting of virtually any pandemic or biological attack for which a neutralizing antibody exists or can be easily isolated," says Wilson. "Further development of this approach for pandemic flu has taken on more urgency in light of the spreading infection in China of the lethal bird strain of H7N9 virus in humans."

At the Ready Influenza infections are the seventh leading cause of death in the United States and result in almost 500,000 deaths worldwide per year, according to the Centers for Disease Control. The emergence of a new influenza pandemic remains a threat that could result in a much loss of life and worldwide economic disruption.

There is also interest by the military in developing an off-the-shelf prophylactic vaccine should soldiers be exposed to weaponized strains of infectious agents in biologic warfare.

Human antibodies with broad neutralizing activity against various influenza strains exist but their direct use as a prophylactic treatment is impractical. Now, yearly flu vaccines are made by growing the flu virus in eggs. The viral envelope proteins on the exterior, namely hemagglutinin, are cleaved off and used as the vaccine, but vary from year to year, depending on what flu strains are prevalent. However, high mutation rates in the proteins result in the emergence of new viral types each year, which elude neutralization by preexisting antibodies in the body (specifically specific receptor binding sites on the virus that are the targets of neutralizing antibodies).

This approach has led to annual vaccinations against seasonal strains of flu viruses that are predicted to emerge during the upcoming season. Strains that arise outside of the human population, for example in domestic livestock, are distinct from those that normally circulate in humans, and can lead to deadly pandemics.

These strains are also not effectively controlled by vaccines developed to human strains, as with the 2009 H1N1 pandemic. The vaccine development time for that strain, and in general, was not fast enough to support vaccination in response to an emerging pandemic.

Knowing this, the Penn team proposed a novel approach that does not require the elicitation of an immune response, which does not provide sufficient breadth to be useful against any strain of flu other than the one for which it was designed, as with conventional approaches.

The Penn approach is to clone into a vector a gene that encodes an antibody that is effective against many strains of flu and to engineer cells that line the nasal passages to express this broadly neutralizing antibody, effectively establishing broad-based efficacy against a wide range of flu strains.

A Broad Approach The rational for targeting nasal epithelial cells for antibody expression was to focus this expression to the site of the body where the virus usually enters the body and replicates which is the nasal and oral mucosa. Antibodies are normally expressed from B lymphocytes so one challenge was to design vectors that could deliver antibody genes to the non- lymphoid respiratory cells of the nasal and lung passages and could express functional antibody protein.

Targeting the respiratory cells was achieved through the use of a vector based on a primate virus -- AAV9 -- which was discovered in the Wilson laboratory and evaluated previously by Limberis for possibly treating patients with cystic fibrosis. The team constructed a genetic payload for AAV9 that expressed an antibody that was showed by other investigators to have broad activity against flu.

Efficacy of the treatment was tested in mice that were exposed to lethal quantities of three strains of H5N1 and two strains of H1N1, all of which have been associated with historic human pandemics (including the infamous H1N1 1918).

Flu virus rapidly replicated in untreated animals all of which needed to be euthanized. However, pretreatment with the AAV9 vector virtually shut down virus replication and provided complete protection against all strains of flu in the treated animals. The efficacy of this approach was also demonstrated in ferrets, which provide a more authentic model of human pandemic flu infection.

"The novelty of this approach is that we're using AAV and we're delivering the prophylactic vaccine to the nose in a non-invasive manner, not a shot like conventional vaccines that passively transfer antibodies to the general circulation," says Limberis.

"There's a long history of using antibodies for cancer and autoimmune disease, but only two have been approved for infectious diseases," notes Tretikova. "This novel technique has allowed for the development of a prophylactic passive vaccine that is cost effective, easily administered, and quickly manufactured."

The team is working with various stakeholders to accelerate the development of this product for pandemic flu and to explore the potential of AAV vectors as generic delivery vehicles for countermeasures of biological and chemical weapons.

The research was supported in part by ReGenX, the Public Health Agency of Canada (#531252), the Canadian Institutes of Health Research (#246355) and the National Institutes of Health (GM083602).

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/TdOOUl4KLCw/130529144242.htm

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Applications for US unemployment aid rise to 354K

WASHINGTON (AP) ? The number of Americans seeking unemployment benefits rose 10,000 last week to a seasonally adjusted 354,000. Still, the level of applications is consistent with steady hiring and remains near a five-year low.

The Labor Department said Thursday that applications increased from a revised 344,000 the previous week, slightly higher than the 340,000 initially reported.

The gains pushed the less volatile four-week average up 6,750 to 347,250, the third straight increase.

Weekly applications are a proxy for layoffs. They have fallen nearly 7 percent since November and touched a five-year low of 338,000 earlier this month.

The decline in applications for unemployment aid has coincided with solid hiring. In the past six months, employers have added an average of 208,000 jobs a month. That's up from an average of only 138,000 in the previous six months.

The unemployment rate has fallen to a four-year low of 7.5 percent, down from 10 percent in October 2009. The drop in unemployment has occurred, in part, because many people have given up looking for work. The government counts people as unemployed only if they are actively searching for a job.

"We can't make too many inferences from one week's results but the trend, overall, still points to improving labor markets," said Jennifer Lee, an economist at BMO Capital Markets.

Five states were unable to report complete data to the Labor Department, a spokesman said, because of the Memorial Day holiday earlier this week. The department estimated figures for those five states. That could mean that last week's figure will be revised more than usual next week when the final data is received.

Nearly 4.6 million Americans were receiving unemployment benefits the week that ended May 11, the latest data available. That's down 25 percent from 6.1 million a year earlier.

A separate report Thursday showed that the economy expanded at a 2.4 percent annual pace in the first three months of the year. That was slightly below an earlier estimate of 2.5 percent but much better than the 0.4 percent pace in the final three months of last year.

Economists expect growth will slow to about 2 percent in the current quarter, as businesses and consumers adjust to tax increases that took effect at the beginning of the year and federal government spending cuts that kicked in March 1.

Two reports this week suggested that the economy is still expanding at a steady pace. Home prices are surging and consumers are more confident. Both trends could encourage more spending in the coming months, providing crucial support for growth.

Consumer confidence jumped in May to the highest level in five years, the Conference Board said Tuesday. Soaring stock prices and Americans' brighter outlook on the job market helped drive the gain.

Home prices jumped nearly 11 percent in March from a year earlier, according to the Standard & Poor's/Case-Shiller home price index, also released Tuesday. That is the biggest gain in seven years.

Higher prices increase homeowners' net worth, which makes them more likely to spend. They can also sustain the housing recovery, by encouraging more would-be buyers to purchase homes before prices rise further.

More buyers are bidding on a tight supply of homes. That's encouraged builders to step up construction, which creates more jobs. Applications for building permits rose to the highest level in five years in April.

The brightening economic picture has raised speculation that the Federal Reserve would dial back its $85 billion a month bond-buying program. The purchases are intended to lower long-term interest rates and encourage more borrowing and spending.

Fed Chairman Ben Bernanke told Congress last week that it was too early to wind down the program. Fed policymakers have said they will continue the purchases until there is substantial improvement in employment.

Source: http://news.yahoo.com/applications-us-unemployment-aid-rise-354k-123655605.html

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Thursday, May 30, 2013

Here's Your Chance to Become One of the First Asteroid Prospectors

Here's Your Chance to Become One of the First Asteroid Prospectors

It was just over a year ago, back in April 2012, that we first learned the intentions of a company known as Planetary Resources: Asteroid mining. As in going into space, finding an asteroid that's not-too-far from Earth, and mining it for precious minerals and/or water which could be used as space-fuel for other missions. In a word: Ambitious.

A couple months later, we learned that Planetary Resources was considering letting your average Joe in on the action by using the crowd-funding site Kickstarter. A little odd for a company whose investors include Google's Larry Page and Eric Schmidt, James Cameron, and Ross Perot Jr, but part of the idea seemed to get people really interested (and, literally, invested) in space exploration, and rumored backer rewards included things being able to take photos with one of the exploratory satellites All has been quiet since last June, but we just got a hot tip that it's now officially official, and the Kickstarter Project has just gone live.


See, in order to mine asteroids, Planetary Resources are going to deploy several different types of spacecraft. The first step is the Arkyd 100, a small, relatively inexpensive satellite with a telescope that will be put into Earth's orbit. These satellite telescopes are what they will use to identify the best potential asteroids. This Kickstarter is doing something unique, though, they are putting the controls of one of Arkyd 100s into your hands.

The lower-end rewards include a space "selfie." For $25 a picture of your choosing will display on the Arkyd's screen, and it will take a picture of itself with the Earth in the background. That doesn't give you any actual control over the Arkyd, but for 25 bucks, that's still pretty damn cool. As you get into higher pledges, you get to stuff like the ability to use the Arkyd to take a picture of anything you want, in space or on Earth. For more money, you can keep track of that spot, or take a series of photos. You can also donate your time to science, or to schools.

The Kickstarter attempting to raise $1,000,000 in 32 days, which is obviously a lot, but hell, we've seen video games reach for (and achieve) $2M goals before. What's interesting is that for that relatively small amount, it seems that Planetary Resources isn't looking to fund its loftier goals (asteroid mining), it seems more that they are trying to cover the costs of giving an open, space satellite to the world, which is something we've never seen before. At a time when NASA budgets are getting slashed like crazy, we're dying to get people more interested in space exploration. By democratizing a part of it, that might just be the spark needed to fuel the imagination of a new generation of scientists. At least we hope so. How many more stockbrokers do we need? [Planetary Resources / Kickstarter]

Source: http://gizmodo.com/heres-your-chance-to-become-one-of-the-first-asteroid-510285942

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Rhode Island Gov. Lincoln Chafee to Become a Democrat

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President Obama today rolled out the welcome mat for Rhode Island Gov. Lincoln Chafee, the Republican-turned-independent who now plans to affiliate with the Democrats before his 2014 re-election run, three Democratic sources told ABC News today.

"I'm delighted to hear that Governor Chafee is joining the Democratic Party," President Obama said in a statement issued through the Democratic National Committee. "For nearly 30 years, Linc Chafee has served his beloved Rhode Island as an independent thinker and leader who's unafraid to reach across party lines to get things done. I enjoyed working with Linc when he was a Republican in the United States Senate, and I look forward to continuing that collaboration on the issues that matter not just to the Democratic Party, but to every American."

White House Press Secretary Jay Carney told reporters at today's daily press briefing, "Governor Chafee's been a longtime supporter of President Obama, and - not as a party member, but as a supporter of the president and his policies both - but I don't have any other response."

Chafee's gubernatorial office in Rhode Island declined to comment.

The governor dropped his affiliation with the Republican Party in 2007, after serving a single Senate term. He won office as a Republican in 2000, then was unseated by Democrat Sheldon Whitehouse in 2006. Chafee was elected governor as an independent in 2010.

"It's not my party anymore," Chafee said at the time.

Chafee's gubernatorial office in Rhode Island declined to comment, but Chafee has notified Democratic Party officials of his decision, the sources said.

The governor dropped his affiliation with the Republican Party in 2007, after serving a single Senate term. He won office as a Republican in 2000, then was unseated by Democrat Sheldon Whitehouse in 2006. Chafee was elected governor as an independent in 2010.

"It's not my party anymore," Chafee said at the time.

Chafee, 60, opposed the invasion of Iraq and cited "permanent deficits," unfunded tax cuts and drilling in the Arctic National Wildlife Refuge as Republican policies he opposed.

He campaigned for President Obama in 2008 and 2012.

"The president welcomes Governor Chafee to the party," White House Press Secretary Jay Carney told reporters at today's daily press briefing. "Governor Chafee's been a longtime supporter of President Obama, and - not as a party member, but as a supporter of the president and his policies both - but I don't have any other response."

Chafee has seen low approval ratings and could enter a competitive Democratic primary field. State Treasurer Gina Raimondo and Providence Mayor Angel Taveras, both Democrats, have reportedly been gearing up to run for the office in 2014.

Also Read

Source: http://news.yahoo.com/rhode-island-gov-lincoln-chafee-become-democrat-201103170--abc-news-politics.html

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News in Brief: Cancer drug damages mouse hearts by slaying helpful cells

Explanation for side effect in people could provide way to avoid it

By Meghan Rosen

Web edition: May 29, 2013

Enlarge

In a false-color image, pericytes (green, top) wrap around tiny blood vessels (colored red) in a mouse heart, sealing up leaks. Treatment with the cancer drug sunitinib wipes out pericytes in the mouse heart (bottom).

Credit: Courtesy of Science Translational Medicine/AAAS

Heart damage from chemotherapy may be due to leaky pipes. Sunitinib, a cancer drug known to harm heart tissue, wipes out cells that seal blood vessels, Vishnu Chintalgattu of the biotech company Amgen and colleagues report May 29 in Science Translational Medicine.

These cells, called pericytes, normally wind around tiny blood vessels, or microvessels, keeping them healthy and plugging leaks like rubber patches glued to bicycle inner tubes.

Researchers examined tissue from drug-treated and untreated mice and noticed that sunitinib stripped pericytes from microvessels in the heart. Without the sheaths of sticky cells, more than twice as much fluid seeped from the microvessels.

Leaking liquid may explain why as many as 28 percent of sunitinib-treated cancer patients end up with heart trouble, the researchers suggest.

But there may be a way to fix the plumbing problem. Thalidomide, the molecule made famous for causing birth defects and now used to treat cancer, can protect pericytes from slaughter by sunitinib, the team reports.

Dosing lab-grown pericytes with only sunitinib killed the cells, but giving them both drugs didn?t seem to do any harm. And when researchers grafted human cancer tissue into mice and treated them with the two drugs, the animals? tumors shrank and their hearts pumped normally.


R. Ehrenberg. Guards of the blood-brain barrier identified. Science News Online, October 13, 2010. [Go to]

L. Biel. Reviving a tired heart. Science News. Vol. 180, October 22, 2011, p. 26. Available online: [Go to]

Source: http://www.sciencenews.org/view/generic/id/350713/title/News_in_Brief_Cancer_drug_damages_mouse_hearts_by_slaying_helpful_cells

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How to enable the new Gmail in a web browser

New Gmail

Google just announced a pretty major update to Gmail, and you should now be to give it a go in the browser, if you so desire. As our pal Paul O'Brien from MoDaCo points out, all you have to do to enable the new tabbed organization is go to the gear icon on the right of the screen and choose "Configure inbox." (If you're using a wrapper like Mailplane, you might need to do this from a traditional browser first, then restart the app.)

Next you'll be asked which tabs you want to use -- primary, social and promotions are checked by default; updates and forums are other options. Once enabled, you'll find e-mails sorted among the tabs. To move e-mails between tabs, just click and drag. (You'll also be asked if you want to continue to get that particular kind of e-mail in the new tab.)

Still no sign of the new Gmail app for Android, which also will bring a new sorting experience. 

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/r0e1jkng5xk/story01.htm

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Most comprehensive analyses of NSAIDs and coxibs

May 29, 2013 ? Researchers have published in the current issue of The Lancet the most comprehensive analyses of the benefits and risks of non-steroidal anti-inflammatory drugs (NSAIDs), which include cyclo-oxygenase-2 inhibitors (coxibs).

Under the direction of the Clinical Trial Service and Epidemiology Studies Unit at the University of Oxford, researchers from around the world conducted a world-wide meta-analyses using individual participant data from 280 trials of NSAIDs vs. placebo and 474 trials of NSAID vs. another NSAID, which involved a total of 353,809 participants and a total of 233,798 person-years. These results address risks and benefits of drugs used for relief of inflammatory arthritis including cardiovascular disease and other relevant outcomes such as gastrointestinal effects.

"The vascular risks of high-dose diclofenac and ibuprofen are comparable to coxibs, while high-dose naproxen is associated with less vascular risk than other NSAIDs," said Charles H. Hennekens, MD, DrPH, the first Sir Richard Doll professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University. "Although NSAIDs increase vascular and gastrointestinal risks, their magnitude can be predicted, which may help guide clinical decision-making."

David J. Bjorkman, MD, MSPH, dean of the Charles E. Schmidt College of Medicine at FAU and a gastroenterologist noted that "these are the most comprehensive analyses ever conducted of the benefits and risks of NSAIDs, which include coxibs, and should help guide healthcare providers in their prescribing patterns."

Hennekens concluded that "from a clinical and policy perspective, the available data suggest that for relief of pain of inflammatory arthritis, naproxen may have the best benefit-to-risk ratio on cardiovascular disease (CVD). In contrast to naproxen, other traditional NSAIDS and coxibs confer similar moderately increased risks of CVD. At present, individual clinical judgments about coxibs and nonselective NSAIDs should not be limited to risks of CVD. They should also include concerns about non-CVD risks, such as gastrointestinal bleeding and other benefits, including improved quality of life resulting from decreases in impairment from musculoskeletal pain syndromes."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/eUVbiOeoOEI/130529190948.htm

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Rob Lowe cast as JFK in National Geographic film

NEW YORK (AP) ? Rob Lowe will portray President John F. Kennedy in a National Geographic film about the former president's 1963 assassination.

The National Geographic Channel said Tuesday that filming for "Killing Kennedy" would begin next month in Richmond, Va. The film is expected to air around the 50th anniversary of the shooting later this year and is based on the book by Bill O'Reilly.

National Geographic already had a hit earlier this year with an adaptation of another of the Fox News Channel anchor's books, "Killing Lincoln."

In addition to Lowe, the movie will feature Ginnifer Goodwin as the first lady and Michelle Trachtenberg as Marina Oswald.

Source: http://news.yahoo.com/rob-lowe-cast-jfk-national-geographic-film-182426122.html

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Tim Cook: Apple has no issue porting its apps to Android

Tim Cook Apple has no issue porting its apps to Android

While it may seem far-fetched that Apple would consider following BlackBerry Messenger's footsteps and bring some of its apps to Android, it turns out that such a move isn't out of the question. "We have no religious issue with porting an Apple app to Android," said Cook in response to whether iCloud should branch out to other platforms. "If it made sense for us to do that, we would do that. You could apply that to every area of Apple." That's far from a guarantee that we'll see apps coded by Cupertino turn up on Google's mobile OS, but it certainly introduces a possibility that would seem uncharacteristic of the company.

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Source: http://www.engadget.com/2013/05/28/tim-cook-apple-has-no-issue-porting-its-apps-to-android/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Wednesday, May 29, 2013

Percy Jackson Sea of Monsters Trailer: Watch Now!

Source: http://www.thehollywoodgossip.com/2013/05/percy-jackson-sea-of-monsters-trailer-watch-now/

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Promise of central bank support lifts world shares

By Richard Hubbard

LONDON (Reuters) - Investors seized on clear pledges of policy support from Japanese and European central banks on Tuesday to drive world shares higher, sending the yen down sharply against the dollar and boosting oil prices.

That put Wall Street on course for a higher open when trading resumes after Monday's Memorial Day holiday, reversing the trend that saw all three major stock indexes end last week in negative territory.

Heightened expectations the U.S. central bank could soon taper its stimulus programme unleashed turbulence across the markets last week, leaving it to central banks in Japan and Europe to reassure investors their liquidity taps remain open.

"There is still some nervousness, but investors are also feeling that equities are the best asset class," Keith Bowman, analyst at Hargreaves Lansdown,

Equity markets around the world hit their highest levels in many years this month due to the cheap funding from the Fed and other central banks. But the comments by Fed chairman Ben Bernanke suggesting a U.S. recovery could bring a shift in policy have made investors question prospects for further gains.

"We have had a significant move higher and now it's time for taking stock and deciding whether we continue to go higher or we are due a correction," Michael Hewson, senior market analyst at CMC Markets said.

The question is being asked most about the Japanese market, where the Nikkei stock index had reached a 5-1/2-year high before dropping 7.3 percent last Thursday - its largest one-day loss since the March 2011 earthquake and tsunami.

The Nikkei steadied on Tuesday, ending 1.2 percent higher after long-serving board member Ryuzo Miyao said the Bank of Japan would fine-tune market operations to ensure its unprecedented easing campaign is not derailed.

European Central Bank officials also weighed in to help ease investor's nerves, sending the broad FTSE Eurofirst 300 index up 1.25 percent by midday, its best day in a month.

ECB Executive Board member Peter Praet said the bank could still cut interest rates further to stimulate the economy if needed. His comment echoed that of ECB Executive Board member Joerg Asmussen on Monday who said the loose policy would stay as long as necessary.

Tuesday's rebound took Germany's DAX up 1.2 percent to near recent record highs. In London, the FTSE 100 index was up 1.6 percent, led by banking stocks.

MSCI's world equity index had risen 0.4 percent by mid-morning, reversing four days of losses.

SAFETY ABANDONED

The dollar rose 1.0 percent to 102.00 yen, up more than a full yen from a two-week low of 100.66 hit on Friday. While against the Swiss franc, another currency seen as a safe haven, the dollar up 0.5 percent to 0.9675 francs.

"The yen and Swiss franc have dropped noticeably this morning, essentially because risk assets seem to be stabilising," said Societe Generale currency strategist Alvin Tan.

The euro was little changed at $1.2940 against the dollar, trading well within its recent range of $1.28-1.32.

Investors also turned away from German government bonds though the talk of future ECB rate cuts lent support. The yield on the 10-year bond was flat at 1.43 percent.

The rally in equity markets and signs of rising Middle East tension lifted oil prices sharply. U.S. crude futures gained 0.8 percent to $94.78 a barrel and Brent rose 1.5 percent to $104.16 a barrel.

"Oil has made gains today on the back of friendly equity markets," said Carsten Fritsch, senior oil analyst at Commerzbank in Frankfurt.

(Additional reporting by Atul Prakash and Anooja Debnath. Editing by Catherine Evans, John Stonestreet, Ron Askew)

Source: http://news.yahoo.com/ecb-boj-support-pledges-boost-world-shares-093937248.html

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Picking up a second language is predicted by ability to learn patterns

May 28, 2013 ? Some people seem to pick up a second language with relative ease, while others have a much more difficult time. Now, a new study suggests that learning to understand and read a second language may be driven, at least in part, by our ability to pick up on statistical regularities.

The study is published in Psychological Science, a journal of the Association for Psychological Science.

Some research suggests that learning a second language draws on capacities that are language-specific, while other research suggests that it reflects a more general capacity for learning patterns. According to psychological scientist and lead researcher Ram Frost of Hebrew University, the data from the new study clearly point to the latter:

"These new results suggest that learning a second language is determined to a large extent by an individual ability that is not at all linguistic," says Frost.

In the study, Frost and colleagues used three different tasks to measure how well American students in an overseas program picked up on the structure of words and sounds in Hebrew. The students were tested once in the first semester and again in the second semester.

The students also completed a task that measured their ability to pick up on statistical patterns in visual stimuli. The participants watched a stream of complex shapes that were presented one at a time. Unbeknownst to the participants, the 24 shapes were organized into 8 triplets -- the order of the triplets was randomized, though the shapes within each triplet always appeared in the same sequence. After viewing the stream of shapes, the students were tested to see whether they implicitly picked up the statistical regularities of the shape sequences.

The data revealed a strong association between statistical learning and language learning: Students who were high performers on the shapes task tended to pick up the most Hebrew over the two semesters.

"It's surprising that a short 15-minute test involving the perception of visual shapes could predict to such a large extent which of the students who came to study Hebrew would finish the year with a better grasp of the language," says Frost.

According to the researchers, establishing a link between second language acquisition and a general capacity for statistical learning may have broad implications.

"This finding points to the possibility that a unified and universal principle of statistical learning can quantitatively explain a wide range of cognitive processes across domains, whether they are linguistic or nonlinguistic," they conclude.

This research was supported by the Israel Science Foundation (159/10) and by the National Institute of Child Health and Human Development (RO1 HD 067364 and PO1HD 01994).

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/JkYFOUSJm24/130528143800.htm

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Aspirin triggered resolvin protects against cognitive decline after surgery

Aspirin triggered resolvin protects against cognitive decline after surgery [ Back to EurekAlert! ] Public release date: 28-May-2013
[ | E-mail | Share Share ]

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Resolvins are molecules naturally produced by the body from omega-3 fatty acids a process that can be jumpstarted by common aspirin. In a new study, published in The FASEB Journal, researchers at Karolinska Institutet describe how resolvins could protect against the cognitive impairment that often affects recovery of surgical and critically ill patients. The study adds new knowledge on how peripheral surgery affects the brain and neuronal function contributing to the processes of cognitive decline.

Hospitalization for surgery or critical illness can lead to cognitive dysfunction in some patients, especially the elderly. This is often reported as inattention, disorganized thinking, altered consciousness and prolonged disruptions in learning and memory functions. The mechanisms whereby surgery and/or anesthesia may lead to cognitive impairment remain unclear, but the researchers behind the current study have previously demonstrated that inflammation and release of pro-inflammatory molecules, like cytokines, play an important role in causing brain inflammation and cognitive decline after surgery.

Today there is no effective treatment for postoperative cognitive dysfunctions. However, the results now presented in The FASEB Journal suggest that it is possible to prevent and treat this condition by turning off and 'resolving' the inflammation that underlies surgery-induced cognitive decline. In the current preclinical study, treatment with a single dose of aspirin-triggered resolvin D1 (AT-RvD1), a substance from the omega-3 fatty acid docosahexaenoic acid (DHA), protected the brain from memory dysfunction after surgery.

The treatment also had an effect on neuronal function when given 24 hours after surgery. In their study, the researchers also further describe how surgery affects brain function in general, contributing to processes of neuroinflammation and memory impairment.

"We report a novel role for AT-RvD1 in restoring memory dysfunction after surgery", says Dr. Niccol Terrando, Assistant Professor at the Department of Physiology and Pharmacology, who lead the study. "It was remarkable that AT-RvD1 displayed such unexpected effects on the central nervous system when administered at very low doses in the systemic circulation using this surgical model."

"Aspirin works as an anti-inflammatory by lowering the levels of prostaglandins and thromboxanes but in the presence of essential omega-3 fatty acids can also increases the body's own production of various lipid mediators, including resolvins like AT-RvD1, which promote resolution of inflammatory processes", says Professor Lars I Eriksson, head of the research group behind these findings at the Section of Anesthesiology and Intensive Care Medicine at Karolinska Institutet. "These molecules, aside from reversing inflammation, also promote healing and tissue regeneration that are of relevance to patient safety and recovery. We hope to apply these therapies to prevent cognitive decline in at-risk surgical patients by translating our findings into patient care."

###

The study was supported by grants from the Swedish Research Council, Thorsten Sderberg Foundation and European Society of Anesthesiology (ESA), amongst others.

Publication: 'Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline', Niccol Terrando, Marta Gmez-Galn, Ting Yang, Mattias Carlstrm, Daniel Gustavsson, Ralph Harding, Maria Lindskog, and Lars I Eriksson, The FASEB Journal, online 24 May 2013, doi:10.1096/fj.13-230276, Vol. 27 September 2013.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Aspirin triggered resolvin protects against cognitive decline after surgery [ Back to EurekAlert! ] Public release date: 28-May-2013
[ | E-mail | Share Share ]

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet

Resolvins are molecules naturally produced by the body from omega-3 fatty acids a process that can be jumpstarted by common aspirin. In a new study, published in The FASEB Journal, researchers at Karolinska Institutet describe how resolvins could protect against the cognitive impairment that often affects recovery of surgical and critically ill patients. The study adds new knowledge on how peripheral surgery affects the brain and neuronal function contributing to the processes of cognitive decline.

Hospitalization for surgery or critical illness can lead to cognitive dysfunction in some patients, especially the elderly. This is often reported as inattention, disorganized thinking, altered consciousness and prolonged disruptions in learning and memory functions. The mechanisms whereby surgery and/or anesthesia may lead to cognitive impairment remain unclear, but the researchers behind the current study have previously demonstrated that inflammation and release of pro-inflammatory molecules, like cytokines, play an important role in causing brain inflammation and cognitive decline after surgery.

Today there is no effective treatment for postoperative cognitive dysfunctions. However, the results now presented in The FASEB Journal suggest that it is possible to prevent and treat this condition by turning off and 'resolving' the inflammation that underlies surgery-induced cognitive decline. In the current preclinical study, treatment with a single dose of aspirin-triggered resolvin D1 (AT-RvD1), a substance from the omega-3 fatty acid docosahexaenoic acid (DHA), protected the brain from memory dysfunction after surgery.

The treatment also had an effect on neuronal function when given 24 hours after surgery. In their study, the researchers also further describe how surgery affects brain function in general, contributing to processes of neuroinflammation and memory impairment.

"We report a novel role for AT-RvD1 in restoring memory dysfunction after surgery", says Dr. Niccol Terrando, Assistant Professor at the Department of Physiology and Pharmacology, who lead the study. "It was remarkable that AT-RvD1 displayed such unexpected effects on the central nervous system when administered at very low doses in the systemic circulation using this surgical model."

"Aspirin works as an anti-inflammatory by lowering the levels of prostaglandins and thromboxanes but in the presence of essential omega-3 fatty acids can also increases the body's own production of various lipid mediators, including resolvins like AT-RvD1, which promote resolution of inflammatory processes", says Professor Lars I Eriksson, head of the research group behind these findings at the Section of Anesthesiology and Intensive Care Medicine at Karolinska Institutet. "These molecules, aside from reversing inflammation, also promote healing and tissue regeneration that are of relevance to patient safety and recovery. We hope to apply these therapies to prevent cognitive decline in at-risk surgical patients by translating our findings into patient care."

###

The study was supported by grants from the Swedish Research Council, Thorsten Sderberg Foundation and European Society of Anesthesiology (ESA), amongst others.

Publication: 'Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline', Niccol Terrando, Marta Gmez-Galn, Ting Yang, Mattias Carlstrm, Daniel Gustavsson, Ralph Harding, Maria Lindskog, and Lars I Eriksson, The FASEB Journal, online 24 May 2013, doi:10.1096/fj.13-230276, Vol. 27 September 2013.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/ki-atr052813.php

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Tuesday, May 28, 2013

Interested in a Cord Taco?

Most cord organizers I’ve seen are made of Velcro or plastic or even fabric, but very few of them are made of leather. ?The Cord Taco 5-Pack from the This is Ground shop on Etsy has five leather cord organizers for the price of a single leather organizer from some companies. ?Each Taco is a [...]

Source: http://the-gadgeteer.com/2013/05/28/interested-in-a-cord-taco/

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Government agrees spending cuts, but most yet to be found

By William James

LONDON (Reuters) - The government said on Tuesday it had secured billions of pounds of spending cuts at government ministries, but still faces an uphill struggle to agree further reductions equivalent to 80 percent of its 11.5 billion pound target.

Battling to reduce a big public deficit, chancellor George Osborne said seven government departments had agreed to cut between 8 and 10 percent from their 2015/16 budgets as part of a government spending review due to be announced on June 26.

But finding the remaining cuts of around 9 billion pounds is likely to strain relations within a Conservative party already divided over Britain's membership of the European Union and gay marriage as ministers try to defend their own budgets.

Britain's Conservative-led government is cutting spending to try to rein in a 114.2 billion pound budget deficit in the face of calls from the International Monetary Fund to spend more now to fund investment and avoid crimping a nascent economic recovery.

Osborne said he had managed to get government departments such as the ministry of justice and the department of energy to agree to the spending cuts ahead of the deadline and that he thought talks to find more reductions were going "pretty well".

"I don't think anyone was expecting me to turn up at the end of May and say I've already agreed seven departments and the actual date when I've got to announce the whole thing is at the end of June," he said in an interview with the BBC.

Osborne on Tuesday ruled out further cuts to a welfare budget that has already undergone a radical overhaul and is a politically-sensitive topic for the left-leaning Liberal Democrats who are the junior partner in a coalition government.

Earlier this year, the government introduced a raft of new welfare cuts, prompting senior Liberal Democrats to try and block any further measures.

RINGFENCED BUDGETS

A decision to protect the education, health and international development budgets from cuts has put other ministers under more pressure to find savings.

Among those departments yet to declare how they will find the savings required are those with some of the biggest budgets such as defence, business and the home office (interior ministry), as well as the body that funds local governments.

Following the killing of a British soldier in London at the hands of two suspected Islamist militants, interior minister Theresa May has said the budget for counter-terrorism police spending should be protected.

Defence secretary Philip Hammond has also publicly resisted a reduction to his 34 billion pound budget, saying significant further cuts would erode Britain's military capability.

The opposition Labour party has been openly critical of the government's austerity strategy and condemned the scale of the cuts the government is targeting.

"(Osborne) seems set to spend the next two years sticking to policies that are badly failing on living standards, growth and even deficit reduction," said Chris Leslie, Labour's spokesman on financial affairs.

(Reporting by Costas Pitas and Andrew Osborn; Writing by William James and William Schomberg; Editing by Catherine Evans)

Source: http://news.yahoo.com/osborne-says-seven-government-departments-agree-spending-cuts-064741561.html

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